FIGURE

Fig. 8

ID

ZDB-FIG-160329-23

Publication

Griffin et al., 2016 - Ferredoxin 1b (Fdx1b) is the essential mitochondrial redox partner for cortisol biosynthesis in zebrafish

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Fig. 8

Morphological phenotype of embryos injected with fdx1 morpholino at 9 hpf.

A, Embryos injected with fdx1-ATG^MO, fdx1-Spl^MO, or fdx1-Ctl^MO were classified based on their progression of epiboly at 9 hpf. Class I represents a normal epiboly, and class II and class III represent delayed movement as indicated by the black arrow. B, Injection of 9 ng of fdx1-Ctl^MO showed 95% of the normal class I phenotype compared with fdx1-ATG^MO-injected embryos, which had 68.9% class II and 18% class III. Coinjection of either fdx1 or fdx1b mRNA with fdx1-ATG^MO partially restored embryos to a class I phenotype.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-fdx1
Knockdown Reagent:	MO1-fdx1
Observed In:	embryo development epiboly involved in gastrulation with mouth forming second
Stage:	90%-epiboly

Phenotype Detail

Acknowledgments

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