FIGURE

Fig. S2

ID

ZDB-FIG-160314-7

Publication

Tulotta et al., 2016 - Inhibition of signaling between human CXCR4 and zebrafish ligands by the small molecule IT1t impairs the formation of triple-negative breast cancer early metastases in a zebrafish xenograft model

Other Figures

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Fig. S2

Cxcr4b does not affect macrophage basal motility and total number. (A) Macrophage tracks in a wild-type Tg(mpeg1:EGFP)^gl22 sibling. (B) Macrophage tracks in a cxcr4b ^-/- Tg(mpeg1:EGFP) ^gl22 sibling. (A′, B′) Bright field images of (A) and (B), respectively show the orientation of the tail fins. Scale bar: 50 µm. (C) Average speed and (D) cumulative distance of macrophages do not differ in WT and Ody larvae at 4 dpf. Statistical significance is assessed using unpaired t-test, ns p> 0.05. (E) Total number of macrophages detected by immunohistochemistry is the same in Ody and WT siblings at 2 dpf. Statistical significance is assessed using Mann-Whitney test, ns p> 0.05. WT: n=57, Ody: n=55.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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