FIGURE

Fig. S1

ID

ZDB-FIG-150803-5

Publication

Bhatia et al., 2015 - Functional Assessment of Disease-Associated Regulatory Variants In Vivo Using a Versatile Dual Colour Transgenesis Strategy in Zebrafish

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Fig. S1

Wild type and variant CRE driven transgene expression patterns in F1 embryos obtained from multiple independent stable transgenic lines.

Dual reporter fluorescence in transgenic F1 embryos from multiple additional independent lines for the SHH-SBE2 (A), SHH-ZRS (B), PAX6-SIMO (C), p300-Pk19 (D) and p300-Pk17 (E) elements. These lines are independent from the ones shown in the main text. The expression sites that are consistent between the multiple transgenic lines for each of the CREs are marked. RH: rostral hypothalamus; CH: caudal hypothalamus; PF: pectoral fin; L: lens; CMZ: ciliary margin zone; OV: otic vesicle; PA2-5: pharyngeal arch 2–5; OC: oral cavity; PQ: palatoquadrate; MC: Meckel’s cartilage; Wt: wild-type; Mut: mutant; hpf: hours post fertilization.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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