FIGURE

Fig. S2

ID

ZDB-FIG-150512-12

Publication

Lee et al., 2015 - IFT46 plays an essential role in cilia development

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Fig. S2

The ift46 intraflagellar transport complex B protein 46 C-terminal domain is sufficient for ift46 function. (A) Diagram of ift46 and deletion mutant structures. Numbers indicate the amino acid positions in ift46 protein. (B) Quantification of the rescue of ift46 morpholino phenotypes by co-injection of human and zebrafish mRNA. Control (n=144), ift46-MO (n=180), IFT46 mRNA+ift46-MO (n=120), zebrafish ift46 mRNA+ift46-MO (n=108). Statistical significance of pairwise comparisons are shown (^***P<0.001; Studentós t-test). (C-H) Representative images of zebrafish larvae following co- injection of ift46-MO and ift46 encoding mRNAs.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 400(2), Lee, M.S., Hwang, K.S., Oh, H.W., Ji-Ae, K., Kim, H.T., Cho, H.S., Lee, J.J., Yeong Ko, J., Choi, J.H., Jeong, Y.M., You, K.H., Kim, J., Park, D.S., Nam, K.H., Aizawa, S., Kiyonari, H., Shioi, G., Park, J.H., Zhou, W., Kim, N.S., Kim, C.H., IFT46 plays an essential role in cilia development, 248-57, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.