FIGURE

Fig. S8

ID

ZDB-FIG-150116-15

Publication

Maeda et al., 2014 - Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2

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Fig. S8

Immunolabeling of Pcdh15a in wild-type siblings and pcdh15a^psi7 mutants. (A) Sequence of the psi7 allele, which encodes splice site mutation causing a frameshift following exon 7. (B) The predicted product is a short N-terminal fragment of Pcdh15a. (C) Immunolabeling with a monoclonal antibody against Pcdh15a. Actin filaments were labeled with rhodamine?phalloidin. (Right) Note the splaying of stereocilia, which is typical for mutants expressing strong alleles of pcdh15a (1). (Scale bar: 5 μm.)

Expression Data

Gene:	pcdh15a
Antibody:	Ab2-pcdh15a
Fish:	WT pcdh15a^psi7/psi7
Anatomical Terms:	hair cell stereocilium tip lateral crista hair cell
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pcdh15a^psi7/psi7
Observed In:	hair cell stereocilium bundle inner ear receptor cell stereocilium organization
Stage:	Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA