FIGURE
            Fig. 4
- ID
- ZDB-FIG-140922-36
- Publication
- Drabsch et al., 2013 - Transforming growth factor beta signalling controls human breast cancer metastasis in a zebrafish xenograft model
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                        Fig. 4
                    
                    
                
                
            
        
        
    
        
            
            
| 
 Smad4 knockdown by shRNA or siRNA in breast cancer cells. (A) MDA-MB-231 with stable knockdown of Smad4 displays a reduced amount of invasion. A representative image from day 6, showing cells located in the collagen fibres of the tail is shown. (B) Transient knockdown of Smad4 in MDA-MB-231 cells was also capable of inhibiting the amount of invasion over 5 days. A representative image from day 5 is shown. Scale bar = 100 μm. Data are representative of three independent experiments with at least 50 embryos per group. Error bars represent standard deviation. | 
                
                    
                        Expression Data
                    
                    
                
                
            
        
        
    
        
            
            
            
            
    
    
                
                    
                        Expression Detail
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Antibody Labeling
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Phenotype Data
                    
                    
                
                
            
        
        
    
        
            
            
            
            
    
    
                
                    
                        Phenotype Detail
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Acknowledgments
                    
                    
                
                
            
        
        
    
        
            
            
                
                    
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      Full text @ Breast Cancer Res.
                
                
            
        
        
    
    
     
        