ZFIN ID: ZDB-FIG-140915-27
Marcelli et al., 2014 - A Dimerized HMX1 Inhibits EPHA6/epha4b in Mouse and Zebrafish Retinas. PLoS One   9:e100096 Full text @ PLoS One
EXPRESSION / LABELING:
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Fish:
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Anatomical Terms:
Stage: Prim-5

Fig. 6

Regulation after hmx1 misexpression in zebrafish.

Expression of hmx1 after heat shock in wt and tg (hsp70:hmx1) embryos (A, B). Hmx1, normally restricted to the nasal retina, lens and ear (arrows in A), was broadly expressed in the transgenic embryo (B). Epha4b expression after heat shock in wt and Tg (hsp70:hmx1) embryos (C–F). Dissected eye showed a strong reduction of epha4b expression in the temporal retina when HMX1 was co-expressed (E, F). Pax6 regulation after HMX1 misexpression in zebrafish. Ocular expression of pax6 in wt (G) was not modified by overexpression of HMX1 in Tg(hsp70:hmx1) embryos (H). Scale bars: 100 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
epha4b WT control Prim-5 optic cup ISH
iro1Tg(AB) heat shock Prim-5 optic cup ISH
hmx1 WT control Prim-5 inner ear ISH
Prim-5 optic cup ISH
Prim-5 solid lens vesicle ISH
iro1Tg(AB) heat shock Prim-5 whole organism ISH
pax6b WT control Prim-5 optic cup ISH
iro1Tg(AB) heat shock Prim-5 optic cup ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One