FIGURE

Fig. 4

ID

ZDB-FIG-140715-77

Publication

Candel et al., 2014 - Tnfa signaling through tnfr2 protects skin against oxidative stress-induced inflammation

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Fig. 4

Tnfr2 deficiency results in increased proliferation of skin keratinocytes.

Zebrafish one-cell krt18:RFP embryos were injected with standard control (Std) or Tnfr2 MOs. (A) Representative frontal (xy) and lateral (yz) tridimensional reconstructions from confocal microscopy images of WIHC of krt18:RFP larvae stained at 3 dpf with anti-RFP (keratinocytes, blue) and anti-phosphorylated H3 (pH 3, proliferation marker) antibodies. (B) Quantification of the number of pH3/RFP⁺ (i.e., proliferating keratinocytes) cells in the CHT area. Each dot represents one single larva, and the mean ± S.E.M. for each group of larvae is also shown. Scale bars, 100 μm. *p<0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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