Fig. 4
- ID
- ZDB-FIG-140428-19
- Publication
- Zhao et al., 2014 - Notch signaling regulates cardiomyocyte proliferation during zebrafish heart regeneration
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Evidence for regeneration of coronary endothelium in Notch-inhibited hearts. (A and B) Representative cardiac sections from heat shocked control (CTRL) (A) and Tg(hsp70:DN-MAML) (B) animals carrying the Tg(kdrl:mCherry) endothelial reporter at 30 dpa. (Insets) Higher magnification views of boxed regions in A and B. Whereas control animals regenerated mCherry+ endocardium and coronary vessels, Tg(hsp70:DN-MAML) hearts harbored mCherry+ endothelial tubes in the nonregenerated region of the heart. The myocardium is autofluorescent in A and B. Fourteen of 14 control and 11 of 11 Tg(hsp70:DN-MAML) hearts demonstrated these phenotypes. |