ZFIN ID: ZDB-FIG-140317-5
Tuz et al., 2014 - Mutations in CSPP1 cause primary cilia abnormalities and Joubert syndrome with or without Jeune asphyxiating thoracic dystrophy. American journal of human genetics   94(1):62-72 Full text @ Am. J. Hum. Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Antibodies:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Long-pec to Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Long-pec to Day 6

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP li3Tg standard conditions Protruding-mouth pancreas IFL
Protruding-mouth pronephric glomerulus IFL
li3Tg + MO1-cspp1a standard conditions Protruding-mouth pancreas IFL
Protruding-mouth pronephric glomerulus IFL
li3Tg + MO2-cspp1a standard conditions Protruding-mouth pancreas IFL
Protruding-mouth pronephric glomerulus IFL
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-arl13b IHC WT standard conditions Long-pec floor plate cilium
IHC WT + MO1-cspp1a + MO1-cspp1b standard conditions Long-pec floor plate cilium
IHC WT + MO1-cspp1b + MO2-cspp1a standard conditions Long-pec floor plate cilium
Ab1-tuba IHC WT standard conditions Long-pec floor plate cilium
IHC WT + MO1-cspp1a + MO1-cspp1b standard conditions Long-pec floor plate cilium
IHC WT + MO1-cspp1b + MO2-cspp1a standard conditions Long-pec floor plate cilium
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-cspp1a + MO1-cspp1b standard conditions Long-pec brain hydrocephalic, abnormal
Long-pec fourth ventricle dilated, abnormal
Long-pec tectal ventricle dilated, abnormal
Long-pec ventricular system dilated, abnormal
Long-pec whole organism curved, abnormal
Day 6 neurocranial trabecula aplastic, abnormal
Day 6 neurocranial trabecula hypoplastic, abnormal
Day 6 pharyngeal arch 3-7 decreased length, abnormal
WT + MO1-cspp1b + MO2-cspp1a standard conditions Long-pec brain hydrocephalic, abnormal
Long-pec fourth ventricle dilated, abnormal
Long-pec tectal ventricle dilated, abnormal
Long-pec ventricular system dilated, abnormal
Long-pec whole organism curved, abnormal
Day 6 neurocranial trabecula aplastic, abnormal
Day 6 neurocranial trabecula hypoplastic, abnormal
Day 6 pharyngeal arch 3-7 decreased length, abnormal
li3Tg + MO1-cspp1a standard conditions Protruding-mouth pronephros cystic, abnormal
li3Tg + MO2-cspp1a standard conditions Protruding-mouth pronephros cystic, abnormal
Full text @ Am. J. Hum. Genet.