FIGURE

Fig. 4

ID

ZDB-FIG-140107-27

Publication

Anton et al., 2013 - Pulse propagation by a capacitive mechanism drives embryonic blood flow

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Fig. 4

The viscous resistance of the ISV flow sets the time scale of the flow decay after heart stops. (A-D) Visualization of the vascular network shape Tg(flk1:eGFP) (A,C) and ISVs with active flow [appearing in pink (false color) after standard deviation projection] (B,D) in controls (A,B) and kdrl knock down (C,D) at 3 dpf. White arrowheads indicate active ISVs. (E) Plot of the simulated experiment. The heart stops at t=15 seconds for both cases. The axes are flow velocity in μm/second versus time for control (red curve), where all the a/vISV are functional and mutants (blue curve) where 85% of the a/vISV are blocked (zero diameter). (F) Example of plots observed for the flow decay after heart stop in one control (red) and one kdrl knockdown (blue) embryo.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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