FIGURE

Fig. 4

ID
ZDB-FIG-131220-45
Publication
Chen et al., 2013 - Cross-species array comparative genomic hybridization identifies novel oncogenic events in zebrafish and human embryonal rhabdomyosarcoma
Other Figures
All Figure Page
Back to All Figure Page
Fig. 4

Figure 4. Knockdown of PLXNA1 impairs migration of human ERMS cells.

Representative images of ERMS cells transfected with gene-specific siRNAs at 0 hr (A, control siRNA; C, CCND2 siRNA; E, HOXC6 siRNA; G, PLXNA1 siRNA) and 22 hrs (B, control siRNA; D, CCND2 siRNA; F, HOXC6 siRNA; H, PLXNA1 siRNA) following gap creation. Scale bar indicates 100 µm. (I) Quantification of data from wound healing assay. Each error bar indicates standard deviation across 5–6 independent replicates. (J) A Transwell migration assay was performed in RD cells that stably express either a control shRNA or two independent PLXNA1 shRNAs. Migration was assessed after 24 hours. Each error bar indicates standard deviation across six fields at 200× magnification. Asterisks denote p<0. 05.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.