FIGURE

Fig. 2

ID

ZDB-FIG-130906-2

Publication

Forbes-Osborne et al., 2013 - Insulinoma-associated 1a (Insm1a) is required for photoreceptor differentiation in the zebrafish retina

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Insm1a-deficient embryos are microphthalmic. Compared to embryos injected with a control morpholino (A, B), insm1a morphants (C, D) displayed mild body torqueing and smaller eyes at 48 hpf. Whereas the eye area was significantly smaller in insm1a morphants (E), body lengths were not significantly different (F), and eye areas remained significantly smaller after controlling for body length (G). (A and C, scale bar=500 μm; B and D, scale bar=100 μm; E?G ⋄=mean; *p<0.0001, t-test; n>12; L, lens; hpf, hours post fertilization; MO, morpholino).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO3-insm1a
Knockdown Reagent:	MO3-insm1a
Observed In:	eye
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 380(2), Forbes-Osborne, M.A., Wilson, S.G., and Morris, A.C., Insulinoma-associated 1a (Insm1a) is required for photoreceptor differentiation in the zebrafish retina, 157-171, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.