FIGURE

Fig. S2

ID

ZDB-FIG-130826-79

Publication

Sasaki et al., 2013 - edn1 and hand2 Interact in Early Regulation of Pharyngeal Arch Outgrowth during Zebrafish Development

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Fig. S2

Loss of function of the programmed cell death gene p53 does not rescue the skeletal phenotype of the edn1 mutant. Flat-mount of cartilage and bone stained with Alcian Blue and Alizarin Red. The skeletal phenotypes of the edn1 single mutant and the edn1;p53 double mutant appear identical, whereas phenotypic rescue would be expected if programmed cell death of pharyngeal arch precursor cells accounted for the edn1 hypoplastic skeleton. Hence the experiment argues against cell death as an explanation for the reduced size of the arches.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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