FIGURE
Fig. S7
- ID
- ZDB-FIG-121205-37
- Publication
- Garnett et al., 2012 - BMP, Wnt and FGF signals are integrated through evolutionarily conserved enhancers to achieve robust expression of Pax3 and Zic genes at the zebrafish neural plate border
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Fig. S7
Constitutively active Lef1 activates pax3a IR1, zic3 E1 and zic3 E2 activity in the absence of cycloheximide. Embryos from the pax3a IR1, zic3 E1 and zic3 E2 transgenic lines were injected with glucocorticoid receptor-tagged Lef1-β-catenin and treated with ethanol (A-C) or dexamethasone (D-F) beginning at tailbud stage. pax3a IR1 exhibited an increase in enhancer activity upon induction of Lef1-β-catinin (D versus. A) (79%, n=19) as did zic3 E1 (E versus B) (45%, n=11) and E2 (F versus C) (100%, n=11). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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