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ZFIN ID: ZDB-FIG-120924-3
Berger et al., 2011 - Evaluation of Exon-Skipping Strategies for Duchenne Muscular Dystrophy Utilizing Dystrophin-deficient Zebrafish. Journal of Cellular and Molecular Medicine   15(12):2643-51 Full text @ J. Cell. Mol. Med.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage: Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Protruding-mouth to Days 7-13

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
dmd WT standard conditions Protruding-mouth muscle IHC
Protruding-mouth somite border IHC
dmdpc2/pc2 + MO3-dmd(TU) standard conditions Protruding-mouth muscle IHC
dmdpc2/pc2 + MO4-dmd + MO5-dmd(TU) standard conditions Protruding-mouth muscle IHC
dmdpc2/pc2(TU) standard conditions Protruding-mouth Not Detected muscle IHC
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
dmdpc2/pc2 + MO3-dmd(TU) standard conditions Protruding-mouth somite myofibril disorganized, abnormal
Protruding-mouth trunk musculature dystrophic, abnormal
Days 7-13 somite myofibril disorganized, abnormal
Days 7-13 somite myofibril mononucleate, abnormal
Days 7-13 somite myofibril necrotic, abnormal
Days 7-13 somite myofibril structure, abnormal
Days 7-13 somite saccular, abnormal
Days 7-13 trunk musculature dystrophic, abnormal
dmdpc2/pc2 + MO4-dmd + MO5-dmd(TU) standard conditions Protruding-mouth somite myofibril organized, normal
Days 7-13 somite myofibril organized, normal
dmdpc2/pc2(TU) standard conditions Protruding-mouth somite myofibril disorganized, abnormal
Protruding-mouth trunk musculature dystrophic, abnormal
Days 7-13 somite myofibril disorganized, abnormal
Days 7-13 somite myofibril mononucleate, abnormal
Days 7-13 somite myofibril necrotic, abnormal
Days 7-13 somite myofibril structure, abnormal
Days 7-13 trunk musculature dystrophic, abnormal
Full text @ J. Cell. Mol. Med.