FIGURE

Fig. 7

ID
ZDB-FIG-120601-69
Publication
Stevenson et al., 2012 - Hypoxia Disruption of Vertebrate CNS Pathfinding through EphrinB2 Is Rescued by Magnesium
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Fig. 7

Magnesium sulfate administration protects against hypoxia-related axon pathfinding defects.

(A) C/L intensity ratios of increasing magnesium concentrations (mM). *p<0.01; ** p<0.001. Error bars SEM. (B, C) Magnesium reduces activation of the hif1α pathway, as shown by decreased igfbp-1 expression following hypoxia and concurrent magnesium exposure from 24–36 hpf. Bright-field images; ventral views, rostral top, scale bar 50 μm. (D) C/L intensity ratios shows rescue by magnesium of DMOG exposure from 24–36 hpf. *p<0.05. Error bars SEM.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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