FIGURE

Fig. 3

ID

ZDB-FIG-120427-7

Publication

Chen et al., 2012 - Zebrafish agr2 is required for terminal differentiation of intestinal goblet cells

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Terminal differentiation of intestinal goblet cells is affected in agr2 morphants.

Significant increases in immature Alcian blue-stained goblet cell numbers were detected in 104- (C, n = 46) and 120-hpf (G, n = 23) agr2 morphants compared to those in either 104- (A, n = 40) and 120-hpf (E, n = 30) wild type or in 104- (B, n = 41) and 120-hpf (F, n = 27) agr2–5 mmMO1 and 5 mmMO2-coinjected embryos. Inset shows a mature and an immature goblet cell. Comparison of both immature and mature goblet cell numbers among agr2 morphants, wild type or agr2–5 mmMO1 and 5 mmMO2-coinjected embryos at 104 and 120 hpf are shown (D, H). A Student′s t-test was conducted to compare immature goblet cell numbers in agr2 morphants with those in wild type or agr2–5 mmMO1 and 5 mmMO2-coinjected embryos. *p<0.001. Scale bars represent 100 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-agr2 + MO2-agr2
Knockdown Reagents:	MO1-agr2 MO2-agr2
Observed In:	goblet cell
Stage Range:	Day 4 to Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One