FIGURE

Fig. 7

ID

ZDB-FIG-120423-13

Publication

Dong et al., 2012 - Intralineage directional notch signaling regulates self-renewal and differentiation of asymmetrically dividing radial glia

Other Figures

All Figure Page

Back to All Figure Page

Fig. 7

The Fate Determinant Mib Is Unequally Segregated to the Apical Daughter in Par-3-Dependent Manner(A) Mib-GFP is detected in the cytosol within the membrane-targeted myr:tdTomato.(B) Mib-GFP is detected in close proximity to the nucleus reporter H2B:mRFP.(C) Mib-GFP colocalizes with Dld.(D) Mib-GFP was unequally segregated into the apical daughter.(E) The unequal segregation of mib-GFP was eliminated by knockdown of par-3.(F) Selected frames of time-lapse live imaging show unequal segregation of Mib-GFP to the apical daughter cell during division.(G) Selected frames of time-lapse live imaging show equal distribution of Mib-GFP in both daughter cells during division in the par-3 morphant.See also Figure S6 and Movies S3 and S4.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Neuron