FIGURE

Fig. 6

ID

ZDB-FIG-120316-87

Publication

Milla et al., 2012 - Yeast-based assay identifies novel Shh/Gli target genes in vertebrate development

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Fig. 6

sfrp2 RNA levels are disturbed in Hh pathway mutants and after pharmacological treatments. (A, A′ ′) In WT embryos, sfrp2 expression is evident in adaxial cells. This expression is significantly down-regulated in yot embryos (B, B′ ′). Pharmacological treatments with pur and cyc show altered expression in pharyngeal arches (asterisk in E, compare C, D and E for different levels of RNA). Anterior is towards left, lateral views are shown. Full lateral views of embryos are shown in A′ and B′.

Expression Data

Gene:	sfrp2
Fish:	WT gli2a^ty17a/ty17a
Conditions:	chemical treatment by environment: Cyclopamine chemical treatment by environment: purmorphamine
Anatomical Terms:	pectoral fin pharyngeal arch 3-7 somite
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT gli2a^ty17a/ty17a
Conditions:	chemical treatment by environment: Cyclopamine chemical treatment by environment: purmorphamine
Observed In:	pharyngeal arch 3-7 somite
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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