Fig. 8

Karlstrom et al., 1996 - Zebrafish mutations affecting retinotectal axon pathfinding
Other Figures
All Figure Page
Back to All Figure Page
Fig. 8

Anti-acetylated tubulin labeling of astray mutants. All panels show a ventral view of the ventral brain commissures at 36 hours of development. (A) In the wild type, the retinal ganglion cell axons grow near the POC (just dorsal to this focal plane). At 36 hours the first RGC axons (arrowheads) have reached the midline and fasciculated with their contralateral homologues. The anterior commissure is at the top of the photo (arrow) and the TPOC axons are lateral in a more dorsal focal plane. (D-D) Three examples of errors made at the midline by RGC growth cones in astray mutants. In all embryos, the POC has formed normally (most easily seen in D, arrow). RGC axons (arrowheads) grow abnormally on the ventral diencephalon. Instead of growing along their contralateral counterparts, RGC axons spread on the ventral diencephalon (B,D). In some cases axons from the two eyes clearly remain separate and appear to avoid each other (C). AC, anterior commissure; POC, postoptic commissure. Scale bars, 25 ┬Ám.

Expression Data
Anatomical Term:
Stage: Prim-25

Expression Detail
Antibody Labeling
Phenotype Data
Observed In:
Stage: Prim-25

Phenotype Detail
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development