FIGURE

Fig. S2

ID

ZDB-FIG-120126-87

Publication

Doll et al., 2011 - Subnuclear development of the zebrafish habenular nuclei requires ER translocon function

Other Figures

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Fig. S2

Transmission electron micrographs of jaw chondrocytes show ER and ECM deficits in sec61al1^c163 mutants. (A, B) Chondrocytes of WT controls have dense ER throughout the cytoplasm (blue arrows) and extensive ECM surrounding chondrocytes (orange brackets). (A′, B′) Endoplasmic reticuli are sparse and discontinuous in sec61al1^c163 mutants and the ECM is reduced in thickness. Dead cells are common in sec61al1^c163 mutant micrographs (pink cross). All scale bars = 2 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sec61a1a^c163/c163 (AB)
Observed In:	chondrocyte endoplasmic reticulum mandibular arch skeleton chondrocyte mandibular arch skeleton extracellular matrix
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 360(1), Doll, C.A., Burkart, J.T., Hope, K.D., Halpern, M.E., and Gamse, J.T., Subnuclear development of the zebrafish habenular nuclei requires ER translocon function, 44-57, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.