FIGURE

Fig. 2

ID

ZDB-FIG-111212-3

Publication

Takeuchi et al., 2007 - Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry

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Fig. 2

Abnormal node morphology in Smarcd3 knockdown embryos. (A–D) Expression of Cer2 and Gdf1 in wild-type and Smarcd3 knockdown (Si) embryos. Red arrowheads show decreased or missing expression. (E–K) Scanning electron microscopy shows high magnification of the node in wild type (E), abnormal node morphology in Smarcd3 knockdown (F and G), and Rbpsuh ^-/- (H) embryos at E7.75. c, crown cells; p, pit cells. Smarcd3 knockdown results in abnormal node morphology, with separated pit cells (F, red asterisks) and abnormally migrated crown cells (yellow circles). Some Smarcd3 mutants also have abnormal leftward shifted nodes in addition (G, red line shows embryonic midline). Abnormal crown cells were seen in Rbpsuh ^-/- embryos (H, yellow circles). (I–L) Expression of Cryptic and Foxa2 in wild-type and Smarcd3 knockdown (Si) embryos.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA