FIGURE

Fig. S3

ID

ZDB-FIG-101115-21

Publication

Scholpp et al., 2009 - Her6 regulates the neurogenetic gradient and neuronal identity in the thalamus

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Fig. S3

Her6 inhibits expression of the proneural gene coe2 and neurog1. Analysis of Her6 function by double ISH. Knock-down of her6 leads to an increase of coe2 expression in the thalamic complex at 30 hpf (a and b). A double in situ hybridization analysis shows that mis-expression of her6 mRNA leads to the down-regulation of neurog1 expression in the thalamus at 24 hpf (c and d; black dashed line). Expression of ascl1a in the ventral part is increased (yellow dashed line). Subsequently, ascl1a expression is increased upon her6 mis-expression at 30 hpf (22/35; f and g). cTh, caudal thalamus; PTh, prethalamus; rTh, rostral thalamus; Th, thalamus.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA