Fig. S1
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- ZDB-FIG-100429-29
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- Ishida et al., 2010 - Phosphorylation of Junb family proteins by the Jun N-terminal kinase supports tissue regeneration in zebrafish
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Onset of regeneration-related gene expression during finfold regeneration. (A–H) Whole-mount in situ hybridization analysis. The expression of regeneration-response genes phlda2 (A), mvp (B), and fn1b (C, D), mmp9 (E–G), and (H) was observed after 1 hpa (E), 3 dpa (A–C, F) or 6 hpa (D, G, H). The induction of mmp9 and fn1b was slightly earlier (approximately 50% of larvae exhibited a low level of gene expression at 1 hpa). In contrast to the expression of these genes, that of dlx5a, one of the epithelial markers ([Kawakami et al., 2004] and [Yoshinari et al., 2009]), was never observed at 6 hpa (H). Gene expression was examined by using more than 10 larvae. (I) A summary of temporal gene expression during regeneration. The red color indicates the unique immediate early expression of jun family genes. The scale bar represents 100 μm in (A). |
Reprinted from Developmental Biology, 340(2), Ishida, T., Nakajima, T., Kudo, A., and Kawakami, A., Phosphorylation of Junb family proteins by the Jun N-terminal kinase supports tissue regeneration in zebrafish, 468-479, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.