FIGURE

Fig. 5

ID

ZDB-FIG-091217-53

Publication

Hammond et al., 2009 - Two populations of endochondral osteoblasts with differential sensitivity to Hedgehog signalling

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Fig. 5

Osteoclasts are active earlier in ptc mutants and later in ihha mutants than in the wild-type situation. (A) Whole mount stained for tartrate resistant acid phosphatases (TRAP). Activity is first present in the fifth branchial arch and in teeth (black arrows). Additionally, by 14 dpf activity can be seen in the Meckel′s cartilage (blue arrow in inset, region enlarged is marked by a dashed box) and operculum (red arrow) in the ptc2^-/- mutant. Dashed box in the top right image denotes the region shown for 10 and 12 dpf. (B-D) Close-up views of the regions of TRAP activity: (B) dissected teeth and fifth branchial arch, (C) neural arch, (D) tail fin. wt, wild type.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ihha^{hu2131/hu2131} ptch2^{hu1602/hu1602}
Observed In:	caudal fin skeleton osteoclast Meckel's cartilage osteoclast neural arch osteoclast opercular flap osteoclast osteoclast differentiation pharyngeal arch 7 skeleton osteoclast
Stage Range:	Days 7-13 to Days 14-20

Phenotype Detail

Acknowledgments

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