FIGURE

Fig. 6

ID

ZDB-FIG-090826-8

Publication

Santoro et al., 2009 - Characterization of vascular mural cells during zebrafish development

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Fig. 6

Vascular mural cells derive from the lateral plate mesoderm but not from the blood or endothelial lineages. Confocal images of transverse sections, at different magnifications, of 80 hpf Tg(flk1:GFP)^s843 wild-type (a and d) or cloche (clo^s5) (b and e) or hands-off (han^s6) (c and f) mutant larvae analyzed for Transgelin expression (red). While wild-type (wt) and clo^s5 mutant larvae show Transgelin-positive cells around both the dorsal aorta and visceral organs, han^s6 mutant larvae completely lack both vascular and visceral MCs. Sections are at the level of the1st-2nd somite. Scale bars, 20 μm. NT, neural tube; DA, dorsal aorta; SB, swim bladder; G, gut; MA, mesenteric artery.

Expression Data

Antibody:	Ab1-tagln
Fish:	s843Tg Df(Chr01:hand2)s6/s6; s843Tg npas4l^s5/s5; s843Tg
Anatomical Term:	vascular associated smooth muscle cell
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	Df(Chr01:hand2)s6/s6; s843Tg
Observed In:	vascular associated smooth muscle cell
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Mechanisms of Development, 126(8-9), Santoro, M.M., Pesce, G., and Stainier, D.Y., Characterization of vascular mural cells during zebrafish development, 638-649, Copyright (2009) with permission from Elsevier. Full text @ Mech. Dev.