FIGURE

Fig. 2

ID

ZDB-FIG-090515-33

Publication

Akimenko et al., 1995 - Anterior duplication of the Sonic hedgehog expression pattern in the pectoral fin buds of zebrafish treated with retinoic acid

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Effects of RA on shh/vhh-1 expression in caudal floor plate cells and notochord. Embryos were treated with RA as in Fig. 1 and were fixed at 56 hr. (A) Residual expression of shh/vhh-1 in floor plate cells at the caudal end of control larvae at 56 hr. At this stage, there is no longer expression of shh/vhh-1 in the notochord. (B and C) Representative examples of shh/vhh-1 expression in RA-treated fish. The caudal-most floor plate cells (arrow) express comparatively higher levels of shh/vhh-1 compared to the same cells in controls. Patches of cells positive for shh/vhh-1 are located in what appears to be an extension of the notochord and/or cells in contact with the extension of the notochord (arrowheads). The caudal neural keel in RA-treated fish is thicker than that in controls. n, notochord; nk, neural keel. Scale bars, 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 170, Akimenko, M.A. and Ekker, M., Anterior duplication of the Sonic hedgehog expression pattern in the pectoral fin buds of zebrafish treated with retinoic acid, 243-247, Copyright (1995) with permission from Elsevier. Full text @ Dev. Biol.