FIGURE

Fig. 10

ID

ZDB-FIG-090513-16

Publication

Vasil et al., 2009 - A complex extracellular sphingomyelinase of Pseudomonas aeruginosa inhibits angiogenesis by selective cytotoxicity to endothelial cells

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Fig. 10

PlcHR acts on endothelial cells independently of erythrocytes wildtype (Tg(Fli:EGFP)) [44], and GATA1 morphants were injected with PlcHR or PlcHR T178A at 48 hpf and observed for phenotypes (n>20 per condition).

PlcHR induced the same effects in morphants as were observed in wild type embryos (C,D), while no effects were noted in either group of embryos when injected with PlcHR T178A (A,B). Prime panels show effects on endothelial cells. (E,F) Depict the lack of circulating blood cells in GATA1 morphants and their presence in wildtype (Tg(fli1:EGFP):Tg(gata1:dsRED)) [44],[45] embryos at the time point in which embryos were scored, respectively. Scale bar indicates 250 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Full text @ PLoS Pathog.