FIGURE

Fig. 6

ID

ZDB-FIG-090428-6

Publication

Faro et al., 2009 - T-Cell Factor 4 (tcf7l2) Is the Main Effector of Wnt Signaling During Zebrafish Intestine Organogenesis

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Fig. 6

Depletion of either Tcf1 or Tcf3 in apc^mcr/mcr genetic background does not rescue expression of differentiation markers in endoderm-derived tissues, but combined depletion recovers expression of l-fabp. Dorsal view of 72 hpf of apc^mcr/mcr (A, E, I), apc^mcr/mcr;tcf1^{hu3238/hu3238} (B, F, J), apc^mcr/mcr;tcf3MO (C, G, K), and apc^mcr/mcr;tcf1^{hu3238/hu3238};tcf3MO (D, H, L) after WISH for i-fabp (A–D), trypsin (E–H), and l-fabp (I–L).

Expression Data

Genes:	fabp2 fabp10a prss1
Fish:	apc^hu745/hu745 apc^hu745/hu745 + MO1-tcf7l1a apc^hu745/hu745; tcf7^{hu3238/hu3238} apc^hu745/hu745; tcf7^{hu3238/hu3238} + MO1-tcf7l1a
Knockdown Reagent:	MO1-tcf7l1a
Anatomical Terms:	exocrine pancreas hepatocyte
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	apc^hu745/hu745 apc^hu745/hu745 + MO1-tcf7l1a apc^hu745/hu745; tcf7^{hu3238/hu3238} apc^hu745/hu745; tcf7^{hu3238/hu3238} + MO1-tcf7l1a
Knockdown Reagent:	MO1-tcf7l1a
Observed In:	endodermal digestive tract morphogenesis exocrine pancreas development hepatocyte differentiation
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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