FIGURE

Fig. 5

ID

ZDB-FIG-090325-1

Publication

Uchida et al., 2009 - An integrated approach for the systematic identification and characterization of heart-enriched genes with unknown functions

Other Figures

Fig. 5

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Fig. 5

Loss-of-function phenotypes after morpholino injections. (A) Effect of zLrrc39 at 108 hpf and (B) zKlhl31 morpholino injections on zebrafish development at 48 hpf, respectively. Lateral views of non-injected control (upper) and morphant (lower) embryos (Tg(myl7:EGFP-HRAS)s883) are shown. The arrow in (A) indicates the pericardial edema in injected zLrrc39 morphant embryos. (C-E) Fluorescent images of heart sections at 48 hpf of control (C), zLrrc39 (D) and zKlhl31 (E) morphants are shown. Cardiomyocytes of zebrafish embryos were marked by expression of EGFP to delineate cellular morphology. Scale bar: 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	s883Tg + MO1-klhl31 s883Tg + MO1-lrrc39
Knockdown Reagents:	MO1-klhl31 MO1-lrrc39
Observed In:	cardiac ventricle embryo development eye heart cardiac muscle cell heart looping muscle pericardial cavity ventral mandibular arch whole organism anterior-posterior axis yolk
Stage Range:	Long-pec to Day 4

Phenotype Detail

Acknowledgments

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