FIGURE

Fig. 5

ID

ZDB-FIG-090324-14

Publication

Goldstein et al., 1998 - Notochord regulates cardiac lineage in zebrafish embryos

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Fig. 5

Notochord ablation redirects cardiac cell fate. The left panel schematics show the site of dye activation relative to the Nkx2.5-expressing zone and the notochord in a 14-somite stage embryo. The middle panels show the location of activated dye as fluorescence images (the white arrow denotes tip of notochord). The right panels show the heart region at prim-5 stage. (A) Normally, cells anterior to the notochord generate progeny in the heart (right panel). (B) Lateral mesoderm cells more posteriorly, next to the notochord, do not normally contribute progeny to the heart. (C) After notochord ablation, cells in the same posterior region as in B now contribute progeny to the heart.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 201, Goldstein, A.M. and Fishman, M.C., Notochord regulates cardiac lineage in zebrafish embryos, 247-252, Copyright (1998) with permission from Elsevier. Full text @ Dev. Biol.