ZFIN ID: ZDB-FIG-080828-61
Arduini et al., 2008 - Zebrafish endzone regulates neural crest-derived chromatophore differentiation and morphology. PLoS One   3(7):e2845 Full text @ PLoS One
Anatomical Term:
Stage: Prim-25
Observed In:
Stage Range: Prim-5 to Prim-25

Fig. 5 Melanophore cell morphology changes in enz mutant embryos.
(A, B) At 27 hpf, wild-type melanophores are large, stellate and well-pigmented (A). enz melanophores are also large and stellate at this stage, but are pale compared to wildtype (B). (C, D) By 31 hpf, enz melanophore begin to transition to a punctate morphology (D), while wild-type melanophores remain large with many processes (C). (E, F) Wild-type (E) and enz mutant (F) embryos at 34.5 hpf. The morphological transition of melanophores in enz homozygotes continues in a rostro-caudal wave and is complete by approximately 48 hpf. (G–J) At 36 hpf, melanosomes are distributed throughout the cytoplasm of wild-type melanophores, reflecting the stellate morphology of these cells (G). (H) dct mRNA (red) is likewise distributed in the extensive processes of wild-type cells (arrowheads). Punctate distribution of melanosomes (I) and dct mRNA (J, red) in enzos18 mutant melanophores is identical at 36 hpf reflecting cell shape change.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
dct WT standard conditions Prim-25 melanocyte ISH
enzos18/os18 standard conditions Prim-25 melanocyte ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
enzb431(AB) standard conditions Prim-5 melanocyte morphology, normal
Prim-5 melanocyte size, normal
Prim-5 pigmentation disrupted, abnormal
Prim-15 melanocyte decreased amount, abnormal
Prim-15 melanocyte punctiform, abnormal
Prim-15 pigmentation disrupted, abnormal
enzos18/os18 standard conditions Prim-25 melanocyte punctiform, abnormal
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