FIGURE

Fig. 5

ID

ZDB-FIG-080620-54

Publication

Li et al., 1997 - A dominant form of inherited retinal degeneration caused by a non-photoreceptor cell-specific mutation

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Fig. 5

Photographs of live embryos (A-D) and histological sections of the brain and retinas (E-H) of wild-type (Left) and homozygousnba (Right) fish. (A and B) Photograph of 2.5-day-old wild-typeand nba embryos. Note the smaller eye (arrow) and blood cellsthat have pooled in the heart (asterisk) in nba fish. (C and D)Acridine orange staining of 2.5-day-old wild-type and nba embryos.Brightly staining apoptotic cells are seen in the retina (arrow)and tectum (arrowhead) in nba fish. Asterisks indicate nonspecificstaining of yolk cells. (E and F) Transverse sections throughthe brain and retina of 2.5-day-old wild-type and nba embryos.Note the darkly stained dying cell in both the retina (arrows)and tectum (arrowheads) in nba fish. (G and H) Transverse sectionsof 3.5-day-old wild-type and nba embryos. By this time most ofthe retinal cells have degenerated (arrows), and the tectum continuousto show evidence of cell death (arrowheads) in nba fish. [Bar= ≈250 μm (A-D) and 100 μm (E-H)].

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA