FIGURE

Fig. 2

ID

ZDB-FIG-080529-7

Publication

Slanchev et al., 2005 - Development without germ cells: The role of the germ line in zebrafish sex differentiation

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Fig. 2

The prokaryotic toxin Kid and antitoxin Kis are functional in zebrafish. (A and B) High concentrations of Kid result in rapid embryonic lethality in embryos injected with kid-nos1 3′-UTR RNA. (C and D) Embryonic development is not affected by high levels of somatically expressed antidote kis-glo UTR RNA. The deleterious effect of 5 pg of Kid on somatic cell development is counteracted efficiently by 1 pg of kis-glo UTR for up to 24 hpf (E), but not at 48 hpf (F). (G and H) A ratio of 1:1 pg of kid-nos1 3′UTR/kis-glo UTR mRNAs allows proper somatic development during the first 2 days of development. (I and J) Quantitative representation of Kid-induced somatic phenotypes during the first 2 days of development.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA