FIGURE

Fig. 6

ID

ZDB-FIG-080424-26

Publication

Andermann et al., 2002 - Neurogenin1 defines zebrafish cranial sensory Ganglia precursors

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

ngn1 morpholino oligonucleotides block differentiation of all cranial ganglia. Control embryos are shown in (A, C, E); ngn1 morpholino injected embryos in (B, D, F). (A, B) Lateral flat mounts of embryos expressing neuroD at 36 h. After ngn1 morpholino injection, neuroD expression is abolished in cranial ganglia (arrows) but not in other regions. (C, D) Lateral view of Hu expression in cranial ganglia at 96 h. In most cases, cranial ganglia are absent, but in some cases, a few neurons remain (arrows). (E, F) Lateral view of Hu expression in the zebrafish trunk at 96 h. The dorsal root ganglia (arrows) are eliminated by ngn1 morpholino injection, while enteric neurons are unaffected. ad, anterodorsal lateral line ganglion; av, anteroventral lateral line ganglion; e, enteric neurons; f, facial ganglion; g, glossopharyngeal ganglion; m, middle lateral line ganglion; o, octaval/statoacoustic ganglion; p, posterior lateral line ganglion; v, vagal ganglia. Bar, 100 μm (A, B) and (E, F); 30 μm (C, D).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 251(1), Andermann, P., Ungos, J., and Raible, D.W., Neurogenin1 defines zebrafish cranial sensory Ganglia precursors, 45-58, Copyright (2002) with permission from Elsevier. Full text @ Dev. Biol.