FIGURE

Fig. 6

ID

ZDB-FIG-071001-46

Publication

Semina et al., 2006 - Mutations in laminin alpha 1 result in complex, lens-independent ocular phenotypes in zebrafish

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Fig. 6

Retinal ganglion cell and photoreceptor defects with loss of Lama1. Brn3c-GFP expression (A–C, green) in retinal ganglion cells from (A) wild-type, (B) lens-ablated, and (C) lama1 morphant eyes. Note the axon routing mistakes in lama1 morphants, but not within lens-ablated eyes. Zpr-1 immunoreactivity (D–F, red) shows photoreceptors in retina from (D) wild-type, (E) lens-ablated, and (F) bal^a69 mutants. Note the ectopic, mis-positioned photoreceptors in the mutants (arrowheads), but not in lens-ablated eyes.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 299(1), Semina, E.V., Bosenko, D.V., Zinkevich, N.C., Soules, K.A., Hyde, D.R., Vihtelic, T.S., Willer, G.B., Gregg, R.G., and Link, B.A., Mutations in laminin alpha 1 result in complex, lens-independent ocular phenotypes in zebrafish, 63-77, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.