ZFIN ID: ZDB-FIG-070914-34
Hagos et al., 2007 - The role of maternal Activin-like signals in zebrafish embryos. Developmental Biology   309(2):245-258 Full text @ Dev. Biol.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Prim-15

Fig. 1 Embryos lacking maternal sqt function have variable defects. Lateral (A, C–E, G, I, K) or ventral (B, D, F, H, J, L) images of live embryos at 30 hpf. The body axis forms normally in wild type (A), Zsqt (C) and Msqt (E) embryos, and none of these embryos are cyclopic (B, D, F), although Zsqt mutants from some crosses display mild cyclopia. Embryos lacking both maternal and zygotic sqt can be classified into three groups depending on their phenotype. The frequency of the phenotypes depends on the genetic background of the mother, as described in the text. The MZsqt embryos depicted in panels G–L are siblings. Class I MZsqt mutants (G, H) are indistinguishable from wild type, while Class II mutants (I, J) display mild cyclopia (J), typical of the previously reported phenotype of Zsqt mutants (Dougan et al., 2003). Class III mutants have reduced dorsal and anterior structures, characterized by reduced (L, arrow) or absent eyes. Anterior is to the left when apparent.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
ndr1cz35/cz35 standard conditions Prim-15 eye aplastic, abnormal
Prim-15 eye fused with eye, abnormal
ndr1cz35/cz35 standard conditions Prim-15 eye fused with eye, abnormal
ndr1cz35/cz35 standard conditions Prim-15 forebrain aplastic, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 309(2), Hagos, E.G., Fan, X., and Dougan, S.T., The role of maternal Activin-like signals in zebrafish embryos, 245-258, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.