FIGURE

Fig. 2

ID

ZDB-FIG-070620-40

Publication

Hans et al., 2007 - Changes in retinoic acid signaling alter otic patterning

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Fig. 2

Application of 20 nM RA leads to widespread ectopic otic induction and to the formation of ectopic otic cells outside of the endogenous ear. (A) Application of 20 nM RA leads to ectopic pax8 expression encompassing the entire preplacodal domain (compare with Fig. 1J,L). (B-D) Embryos treated with 20 nM RA display ectopic patches of cells that express the otic marker stm and form enlarged vesicles. (C,D) Higher magnifications of B show the epithelial structure of these patches. Dorsal views with anterior towards the top. Scale bar: 35 µm for A; 50 µm for B; 10 µm for C,D.

Expression Data

Genes:	pax8 stm
Fish:	AB
Condition:	chemical treatment: all-trans-retinoic acid
Anatomical Terms:	non neural ectoderm otic placode otic vesicle
Stage Range:	5-9 somites to 26+ somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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