FIGURE

Fig. 2

ID

ZDB-FIG-060216-8

Publication

Marlow et al., 1998 - Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish

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Fig. 2

kny^m119 tri^m209 double-mutant embryos exhibit additive defects in convergent extension during somitogenesis and 1 dpf, and a synergistic cyclopia defect, compared to single mutants. (A, C, E, G) Dissecting microscope images, lateral view of live embryos at 30 hpf. The length of the embryo is decreased in kny^m119 (C) and tri^m209 (E) mutants and dramatically decreased in the double mutant (G) compared to wild type (A). Abnormal shape of the yolk cell and cyclopia are seen in the double mutant (G, inset). (B, D, F, H) Dorsal views of live embryos at 13 hpf using Nomarski optics. The mediolateral width and AP extension of somites (s), notochord (n), and neural keel (nk) are affected in an additive fashion in double mutants (H) compared to kny^m119 (D) and tri^m209 (F) single-mutant embryos. fb, forebrain; hb, hindbrain; mb, midbrain; mb/hb, midbrain–hindrain boundary; ye, yolk extension.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gpc4^m119; vangl2^m209 (AB)
Observed In:	eye neural keel notochord somite whole organism yolk
Stage Range:	5-9 somites to Prim-15

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, volume 203, Marlow, F., Zwartkruis, F., Malicki, J., Neuhauss, S.C.F., Abbas, L., Weaver, M., Driever, W., and Solnica-Krezel, L., Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish, 382-399, Copyright 1998, with permission from Elsevier.

Reprinted from Developmental Biology, 203, Marlow, F., Zwartkruis, F., Malicki, J., Neuhauss, S.C.F., Abbas, L., Weaver, M., Driever, W., and Solnica-Krezel, L., Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish, 382-399, Copyright (1998) with permission from Elsevier. Full text @ Dev. Biol.