FIGURE

Fig. 10

ID

ZDB-FIG-050711-15

Publication

Perkins et al., 2005 - dazed gene is necessary for late cell type development and retinal cell maintenance in the zebrafish retina

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Fig. 10

Constant light rearing exacerbates cell death in dazed mutants. A: Wild-type (WT) retinas did not exhibit defects after constant light treatment. B: Retinas from dazed mutants raised under constant lighting displayed widespread cell death in all cell layers and large holes in the photoreceptor layer both centrally and peripherally. C: Wild-type retinas from animals raised in constant darkness appeared slightly developmentally delayed, but degeneration was not observed. D: Dark-reared dazed retinas degenerate. Pyknotic cells were found in the photoreceptor layer, and acellular holes were seen at the marginal zones as in animals raised under cyclic light. Scale bar = 70 μm in D (applies to A-D).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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