CRISPR

CRISPR1-scamp5a

ID

ZDB-CRISPR-260105-3

Name

CRISPR1-scamp5a

Previous Names

None

Target

scamp5a (1)

Sequence

5' - GGCTGTCTAGCATGGATGTG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The PAM site was "CGG" at the 3' end.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
hzu302	scamp5a

Expression

Gene expression in Wild Types + CRISPR1-scamp5a

No data available

Phenotype

Phenotype resulting from CRISPR1-scamp5a

No data available

Phenotype of all Fish created by or utilizing CRISPR1-scamp5a

Phenotype	Fish	Conditions	Figures
brain dopaminergic neuron th expression spatial pattern, ameliorated	scamp5a^{hzu302/hzu302} (AB)	chemical treatment by environment: anthra[1,9-cd]pyrazol-6(2H)-one	Fig. 8 from Liu et al., 2025
brain rac3b expression increased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 7 from Liu et al., 2025
brain dopaminergic neuron th expression decreased distribution, abnormal	scamp5a^{hzu302/hzu302} (AB)	control	Fig. 6 , Fig. 8 from Liu et al., 2025
brain Ab3-bad labeling increased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 6 from Liu et al., 2025
swimming behavior process quality, ameliorated	scamp5a^{hzu302/hzu302} (AB)	altered light dark cycle, chemical treatment by environment: L-dopa	Fig. 5 from Liu et al., 2025
brain jund expression increased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 7 from Liu et al., 2025
brain bcl2b expression decreased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 6 from Liu et al., 2025
brain Ab8-bcl2 labeling decreased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 6 from Liu et al., 2025
brain mapk8ip2 expression increased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 7 from Liu et al., 2025
brain rac3a expression increased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 7 from Liu et al., 2025
brain mapk10 expression increased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 7 from Liu et al., 2025
brain th expression decreased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	control	Fig. 6 , Fig. 8 from Liu et al., 2025
brain th expression amount, ameliorated	scamp5a^{hzu302/hzu302} (AB)	chemical treatment by environment: anthra[1,9-cd]pyrazol-6(2H)-one	Fig. 8 from Liu et al., 2025
brain bada expression increased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 6 from Liu et al., 2025
brain casp3b expression increased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 6 from Liu et al., 2025
whole organism decreased length, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 4 from Liu et al., 2025
brain dopamine decreased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 5 from Liu et al., 2025
brain apoptotic process increased process quality, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 6 from Liu et al., 2025
brain Ab29-casp3 labeling increased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 6 from Liu et al., 2025
brain atf4b expression increased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 7 from Liu et al., 2025
whole organism viability, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 4 from Liu et al., 2025
swimming behavior process quality, ameliorated	scamp5a^{hzu302/hzu302} (AB)	altered light dark cycle, chemical treatment by environment: pramipexole	Fig. 5 from Liu et al., 2025
thigmotaxis decreased process quality, abnormal	scamp5a^{hzu302/hzu302} (AB)	control	Fig. 5 from Liu et al., 2025
swimming behavior decreased process quality, abnormal	scamp5a^{hzu302/hzu302} (AB)	altered light dark cycle	Fig. 5 from Liu et al., 2025
brain fosab expression increased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 7 from Liu et al., 2025
brain jun expression increased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 7 from Liu et al., 2025
brain casp8 expression increased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 6 from Liu et al., 2025
whole organism dead, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 4 from Liu et al., 2025
brain bcl2a expression decreased amount, abnormal	scamp5a^{hzu302/hzu302} (AB)	standard conditions	Fig. 6 from Liu et al., 2025

Citations