CRISPR

CRISPR1-fstl1a

ID

ZDB-CRISPR-250410-10

Name

CRISPR1-fstl1a

Previous Names

None

Target

fstl1a (1)

Sequence

5' - GGGAGCTGGGAGAGAATGTT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The first "G" was added.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf4105	fstl1a

Expression

Gene expression in Wild Types + CRISPR1-fstl1a

No data available

Phenotype

Phenotype resulting from CRISPR1-fstl1a

Phenotype	Fish	Figures
tail bud malformed, abnormal	WT + CRISPR1-fstl1a	Fig. 2 from Guggeri et al., 2024
whole organism curved, abnormal	WT + CRISPR1-fstl1a	Fig. 2 from Guggeri et al., 2024
whole organism dorsal/ventral pattern formation disrupted, abnormal	WT + CRISPR1-fstl1a	Fig. 2 from Guggeri et al., 2024

Phenotype of all Fish created by or utilizing CRISPR1-fstl1a

Phenotype	Fish	Conditions	Figures
visceral fat pparg expression decreased amount, abnormal	fstl1a^{zf4105/zf4105}	high fat	Fig. 5 from Guggeri et al., 2024
Kupffer's vesicle 9+0 non-motile cilium increased length, abnormal	fstl1a^{zf4105/zf4105}	standard conditions	Fig. 2 from Guggeri et al., 2024
visceral fat znf423 expression increased amount, abnormal	fstl1a^{zf4105/zf4105}	high fat	Fig. 5 from Guggeri et al., 2024
visceral fat fstl1a expression decreased amount, abnormal	fstl1a^{zf4105/zf4105}	standard conditions	Fig. 3 from Guggeri et al., 2024
whole organism fstl1a expression decreased amount, abnormal	fstl1a^{zf4105/zf4105}	standard conditions	Fig. 2 from Guggeri et al., 2024
visceral fat adipoqb expression amount, ameliorated	fstl1a^{zf4105/zf4105}	high fat	Fig. 5 from Guggeri et al., 2024
visceral fat cebpa expression decreased amount, abnormal	fstl1a^{zf4105/zf4105}	high fat	Fig. 5 from Guggeri et al., 2024
visceral fat ptch1 expression increased amount, abnormal	fstl1a^{zf4105/zf4105}	high fat	Fig. 5 from Guggeri et al., 2024
adipose tissue development disrupted, abnormal	fstl1a^{zf4105/zf4105}	standard conditions	Fig. 3 from Guggeri et al., 2024
visceral fat fabp4a expression amount, ameliorated	fstl1a^{zf4105/zf4105}	high fat	Fig. 5 from Guggeri et al., 2024
whole organism curved, abnormal	WT + CRISPR1-fstl1a	standard conditions	Fig. 2 from Guggeri et al., 2024
tail bud malformed, abnormal	WT + CRISPR1-fstl1a	standard conditions	Fig. 2 from Guggeri et al., 2024
whole organism dorsal/ventral pattern formation disrupted, abnormal	WT + CRISPR1-fstl1a	standard conditions	Fig. 2 from Guggeri et al., 2024

Citations