CRISPR

CRISPR5-il11a

ID

ZDB-CRISPR-250401-1

Name

CRISPR5-il11a

Previous Names

None

Target

il11a (1)

Sequence

5' - GGATCAAGTGTTACTCGCTC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The PAM site was "AGG" at the 3' end.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
uwk25Tg	il11a

Expression

Gene expression in Wild Types + CRISPR5-il11a

No data available

Phenotype

Phenotype resulting from CRISPR5-il11a

No data available

Phenotype of all Fish created by or utilizing CRISPR5-il11a

Phenotype	Fish	Conditions	Figures
cardiac ventricle regenerating tissue EGFP expression increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; ci5Tg/ci5Tg	resection: cardiac ventricle	Fig. 1 from Shin et al., 2024
cardiac ventricle cardiac mesenchymal cell EGFP expression increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; em15Tg/em15Tg	standard conditions	Fig. 3 from Shin et al., 2024
cardiac ventricle peripheral region EGFP expression increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; em15Tg/em15Tg	standard conditions	Fig. 3 from Shin et al., 2024
epicardium Ab2-postn labeling increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; pd108Tg/pd108Tg	chemical treatment by environment: tamoxifen	Fig. 4 from Shin et al., 2024
epicardium ab7-mapk labeling increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; pd108Tg/pd108Tg	chemical treatment by environment: tamoxifen	Fig. 4 from Shin et al., 2024
cardiac ventricle regenerating tissue EGFP expression increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; pd108Tg/pd108Tg	resection: cardiac ventricle	Fig. 1 from Shin et al., 2024
epicardium mCherry expression increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; pd108Tg/pd108Tg	chemical treatment by environment: tamoxifen	Fig. 4 from Shin et al., 2024
cardiac ventricle blood vessel increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; y1Tg/y1Tg	standard conditions	Fig. 3 from Shin et al., 2024
cardiac ventricle peripheral region EGFP expression increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; y1Tg/y1Tg	standard conditions	Fig. 3 from Shin et al., 2024
cardiac ventricle blood vessel EGFP expression increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; y1Tg/y1Tg	standard conditions	Fig. 3 from Shin et al., 2024
epicardium surf1 expression increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; y1Tg/y1Tg	resection: cardiac ventricle	Fig. 3 from Shin et al., 2024
epicardium surf1 expression increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; y1Tg/y1Tg	standard conditions	Fig. 3 from Shin et al., 2024
epicardium thsd7aa expression increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; y1Tg/y1Tg	standard conditions	Fig. 3 from Shin et al., 2024
epicardium angptl2a expression increased amount, abnormal	il11a^{uwk25Tg/uwk25Tg}; y1Tg/y1Tg	resection: cardiac ventricle	Fig. 3 from Shin et al., 2024
cardiac ventricle peripheral region EGFP expression increased amount, abnormal	col12a1b^{wcm108Tg/wcm108Tg}; il11a^{uwk25Tg/uwk25Tg}; pd108Tg/pd108Tg	standard conditions	Fig. 3 from Shin et al., 2024
epicardium EGFP expression increased amount, abnormal	col12a1b^{wcm108Tg/wcm108Tg}; il11a^{uwk25Tg/uwk25Tg}; pd108Tg/pd108Tg	standard conditions	Fig. 3 from Shin et al., 2024

Citations