CRISPR

CRISPR10-piezo1

ID

ZDB-CRISPR-241021-2

Name

CRISPR10-piezo1

Previous Names

None

Target

Sequence

5' - GATGTGTGCCTCTCAGCAG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genome Build: GRCz11Chromosome: 7

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ion204dTg	piezo1

Expression

Gene expression in Wild Types + CRISPR10-piezo1

No data available

Phenotype

Phenotype resulting from CRISPR10-piezo1

No data available

Phenotype of all Fish created by or utilizing CRISPR10-piezo1

Phenotype	Fish	Conditions	Figures
brain vasculature pericyte GFP expression decreased amount, abnormal	pdgfrb^{ion33dTg/ion33dTg}; piezo1^{ion204dTg/ion204dTg}; c369Tg/c369Tg; s898Tg/s898Tg; um13Tg/um13Tg	chemical treatment by environment: yoda 1	Fig. 3 from Zi et al., 2024
brain vasculature pericyte GFP expression decreased amount, abnormal	pdgfrb^{ion33dTg/ion33dTg}; piezo1^{ion204dTg/ion204dTg}; c369Tg/c369Tg; s898Tg/s898Tg; um13Tg/um13Tg	chemical treatment by environment: Epinephrine bitartrate	Fig. 3 from Zi et al., 2024
brain vasculature pericyte GFP expression decreased amount, abnormal	pdgfrb^{ion33dTg/ion33dTg}; piezo1^{ion204dTg/ion204dTg}; c369Tg/c369Tg; s898Tg/s898Tg; um13Tg/um13Tg	standard conditions	Fig. 3 from Zi et al., 2024
pericyte cell division decreased frequency, abnormal	pdgfrb^{ion33dTg/ion33dTg}; piezo1^{ion204dTg/ion204dTg}; c369Tg/c369Tg; s898Tg/s898Tg; um13Tg/um13Tg	standard conditions	Fig. 3 from Zi et al., 2024
midbrain blood vessel DsRedx expression increased amount, abnormal	pdgfrb^{ion33dTg/ion33dTg}; piezo1^{ion204dTg/ion204dTg}; c369Tg/c369Tg; s898Tg/s898Tg; um13Tg/um13Tg	standard conditions	Fig. 3 from Zi et al., 2024

Citations

Include unpublished citations

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