CRISPR

CRISPR10-sox10

ID

ZDB-CRISPR-240207-12

Name

CRISPR10-sox10

Previous Names

None

Target

sox10 (1)

Sequence

5' - GGGTCGTGGTGACCTAGTTT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ci3020	sox10

Expression

Gene expression in Wild Types + CRISPR10-sox10

No data available

Phenotype

Phenotype resulting from CRISPR10-sox10

No data available

Phenotype of all Fish created by or utilizing CRISPR10-sox10

Phenotype	Fish	Conditions	Figures
whole organism calcium atom decreased amount, abnormal	sox10^{ci3020/ci3020}	standard conditions	Fig. 2. , Fig. 7. from Gjorcheska et al., 2025
NaK ionocyte decreased amount, abnormal	sox10^{ci3020/ci3020}	standard conditions	Fig. 7. from Gjorcheska et al., 2025
pigmentation absent process, abnormal	sox10^{ci3020/ci3020}	standard conditions	Fig. 7. from Gjorcheska et al., 2025
whole organism stc1l expression increased amount, abnormal	sox10^{ci3020/ci3020}	standard conditions	Fig. 5. from Gjorcheska et al., 2025
ionocyte decreased amount, abnormal	sox10^{ci3020/ci3020}	standard conditions	Fig. 4. from Gjorcheska et al., 2025
whole organism calcium atom decreased amount, abnormal	sox10^{ci3020/ci3020}	chemical treatment by environment: calcium dichloride	Fig. 2. from Gjorcheska et al., 2025
ionocyte igfbp5a expression decreased amount, abnormal	sox10^{ci3020/ci3020}	standard conditions	Fig. 4. from Gjorcheska et al., 2025
bone mineralization delayed, abnormal	sox10^{ci3020/ci3020}	standard conditions	Fig. 1. , Fig. 7. from Gjorcheska et al., 2025
bone mineralization delayed, abnormal	sox10^{ci3020/ci3020}	chemical treatment by environment: calcium dichloride	Fig. 2. from Gjorcheska et al., 2025
inner ear malformed, abnormal	sox10^{ci3020/ci3020}	standard conditions	Fig. 7. from Gjorcheska et al., 2025
corpuscles of Stannius increased size, abnormal	sox10^{ci3020/ci3020}	standard conditions	Fig. 6. from Gjorcheska et al., 2025
corpuscles of Stannius stc1l expression increased amount, abnormal	sox10^{ci3020/ci3020}	standard conditions	Fig. 5. from Gjorcheska et al., 2025
ionocyte trpv6 expression decreased amount, abnormal	sox10^{ci3020/ci3020}	standard conditions	Fig. 4. from Gjorcheska et al., 2025
ceratobranchial cartilage absent, abnormal	sox10^ci3020/+; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022
hyomandibula malformed, abnormal	sox10^ci3020/+; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022
ectomesenchyme sox9a expression decreased amount, abnormal	sox10^{ci3020/ci3020}; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022
ectomesenchyme dlx2a expression decreased amount, abnormal	sox10^{ci3020/ci3020}; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022
ectomesenchyme twist1a expression decreased amount, abnormal	sox10^{ci3020/ci3020}; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022
ceratobranchial cartilage absent, abnormal	sox10^{ci3020/ci3020}; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022
hyomandibula malformed, abnormal	sox10^{ci3020/ci3020}; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022
heart edematous, abnormal	sox10^{ci3020/ci3020}; stc1l^mi610/mi610	standard conditions	Fig. 7. from Gjorcheska et al., 2025
pigmentation absent process, abnormal	sox10^{ci3020/ci3020}; stc1l^mi610/mi610	standard conditions	Fig. 7. from Gjorcheska et al., 2025
whole organism calcium atom amount, ameliorated	sox10^{ci3020/ci3020}; stc1l^mi610/mi610	standard conditions	Fig. 7. from Gjorcheska et al., 2025
inner ear malformed, abnormal	sox10^{ci3020/ci3020}; stc1l^mi610/mi610	standard conditions	Fig. 7. from Gjorcheska et al., 2025
NaK ionocyte amount, ameliorated	sox10^{ci3020/ci3020}; stc1l^mi610/mi610	standard conditions	Fig. 7. from Gjorcheska et al., 2025
bone mineralization process quality, ameliorated	sox10^{ci3020/ci3020}; stc1l^mi610/mi610	standard conditions	Fig. 7. from Gjorcheska et al., 2025
hyomandibula present, ameliorated	nr2f2^{ci3005/ci3005}; sox10^ci3020/+; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022
ceratobranchial cartilage present, ameliorated	nr2f2^{ci3005/ci3005}; sox10^ci3020/+; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022
ectomesenchyme sox9a expression decreased amount, abnormal	nr2f2^{ci3005/ci3005}; sox10^{ci3020/ci3020}; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022
hyomandibula present, ameliorated	nr2f2^{ci3005/ci3005}; sox10^{ci3020/ci3020}; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022
ectomesenchyme dlx2a expression decreased amount, abnormal	nr2f2^{ci3005/ci3005}; sox10^{ci3020/ci3020}; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022
ectomesenchyme twist1a expression decreased amount, abnormal	nr2f2^{ci3005/ci3005}; sox10^{ci3020/ci3020}; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022
ceratobranchial cartilage present, ameliorated	nr2f2^{ci3005/ci3005}; sox10^{ci3020/ci3020}; nr2f5^{ci3000/ci3000}	standard conditions	Fig. 4 from Okeke et al., 2022

Citations