CRISPR

CRISPR16-tp53

ID
ZDB-CRISPR-230411-4
Name
CRISPR16-tp53
Previous Names
None
Target
Sequence
5' - GGGTGGACGTTGCCCCTCCAC - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 5
Constructs
Genomic Features
Genomic Feature Affected Genomic Regions
zf3638 tp53
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Expression
Gene expression in Wild Types + CRISPR16-tp53
No data available
Phenotype
Phenotype resulting from CRISPR16-tp53
No data available
Phenotype of all Fish created by or utilizing CRISPR16-tp53
Phenotype Fish Conditions Figures
liver ab11-tp53 labeling spatial pattern, abnormal tp53zf3638/zf3638 standard conditions Fig. 2 with image from Luo et al., 2021
liver ab11-tp53 labeling decreased amount, abnormal tp53zf3638/zf3638 standard conditions Fig. 2 with image from Luo et al., 2021
liver tp53 expression decreased amount, abnormal ptenazf3641/zf3641; ptenbzf3644/zf3644; tp53zf3638/zf3638 standard conditions Fig. 4 with image from Luo et al., 2021
vasculature hepatocellular carcinoma neoplastic, invasive, abnormal ptenazf3641/zf3641; ptenbzf3644/zf3644; tp53zf3638/zf3638 standard conditions Fig. 4 with image from Luo et al., 2021
liver hepatocellular carcinoma neoplastic, malignant, ameliorated ptenazf3641/zf3641; ptenbzf3644/zf3644; tp53zf3638/zf3638 chemical treatment by environment: MK-2206 Fig. 6 with image from Luo et al., 2021
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Citations
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