CRISPR

CRISPR1-lrrk2,slc2a13b

ID
ZDB-CRISPR-230208-1
Name
CRISPR1-lrrk2,slc2a13b
Previous Names
  • CRISPR4-lrrk2
Targets
Sequence
5' - GGGATGTTAATGTGTCAACA - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
The PAM site was "TGG" at the 3 end.
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 25
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
tud113 lrrk2
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Expression
Gene expression in Wild Types + CRISPR1-lrrk2,slc2a13b
No data available
Phenotype
Phenotype resulting from CRISPR1-lrrk2,slc2a13b
No data available
Phenotype of all Fish created by or utilizing CRISPR1-lrrk2,slc2a13b
Phenotype Fish Conditions Figures
brain monoamine oxidase activity increased magnitude, abnormal lrrk2tud113/tud113 standard conditions Fig 4 with image from Suzzi et al., 2021
paraventricular organ ab1-th labeling decreased amount, abnormal lrrk2tud113/tud113 standard conditions Fig 3 with image from Suzzi et al., 2021
telencephalon ab1-th labeling decreased amount, abnormal lrrk2tud113/tud113 standard conditions Fig 3 with image from Suzzi et al., 2021
hindbrain cell death increased frequency, abnormal lrrk2tud113/tud113 standard conditions Fig 2 with image from Suzzi et al., 2021
telencephalon cell death increased frequency, abnormal lrrk2tud113/tud113 standard conditions Fig 2 with image from Suzzi et al., 2021
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Citations
TSV
1 - 1 of 1
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