CRISPR

CRISPR1-npc2.1

ID
ZDB-CRISPR-220125-6
Name
CRISPR1-npc2.1
Previous Names
None
Target
Sequence
5' - GGACTACAGAGTGCTCGGCG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 17
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
y536 npc2.1
y537 npc2.1
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Expression
Gene expression in Wild Types + CRISPR1-npc2.1
No data available
Phenotype
Phenotype resulting from CRISPR1-npc2.1
No data available
Phenotype of all Fish created by or utilizing CRISPR1-npc2.1
Phenotype Fish Conditions Figures
otolith absent, abnormal npc2.1y536/y536 (EKW) standard conditions Fig. 5 with image,  Fig. 6 with image from Tseng et al., 2021
whole organism decreased length, abnormal npc2.1y536/y536 (EKW) standard conditions Fig. 4 with image from Tseng et al., 2021
head decreased size, abnormal npc2.1y536/y536 (EKW) standard conditions Fig. 5 with image,  Fig. 6 with image from Tseng et al., 2021
otic vesicle cytoplasm decreased volume, abnormal npc2.1y536/y536 (EKW) standard conditions Fig. S7 from Tseng et al., 2021
post-vent region kinked, ameliorated npc2.1y536/y536 (EKW) chemical treatment: beta-cyclodextrin Fig. 6 with image from Tseng et al., 2021
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Citations
TSV
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