CRISPR

CRISPR1-mfap4

ID

ZDB-CRISPR-210309-1

Name

CRISPR1-mfap4

Previous Names

None

Targets

mfap4.1 (1)
mfap4.2 (1)
mfap4.3 (1)

Sequence

5' - GTGACTGTACATCCATGCCC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

View all 3 target locations

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
imb5	mfap4.2

Expression

Gene expression in Wild Types + CRISPR1-mfap4

No data available

Phenotype

Phenotype resulting from CRISPR1-mfap4

No data available

Phenotype of all Fish created by or utilizing CRISPR1-mfap4

Phenotype	Fish	Conditions	Figures
erythroid progenitor cell gata1a expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
granulocyte monocyte progenitor cell spi1b expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
common myeloid progenitor spi1b expression increased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
macrophage lcp1 expression increased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
hematopoietic multipotent progenitor cell gata2a expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
macrophage mfap4.2 expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 2 from Ong et al., 2020
neutrophil mpx expression increased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
granulocyte cpa5 expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
whole organism mfap4.2 expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 2 from Ong et al., 2020
lymphoid progenitor cell ikzf1 expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
macrophage EGFP expression decreased amount, abnormal	mfap4.2^imb5/imb5; gl22Tg/gl22Tg	amputation: caudal fin	Figure 3 from Ong et al., 2020
regenerating fin macrophage EGFP expression decreased amount, abnormal	mfap4.2^imb5/imb5; gl22Tg/gl22Tg	amputation: caudal fin	Figure 3 from Ong et al., 2020
macrophage EGFP expression decreased amount, abnormal	mfap4.2^imb5/imb5; gl22Tg/gl22Tg	standard conditions	Figure 3 from Ong et al., 2020
regenerating fin neutrophil migration increased rate of occurrence, abnormal	mfap4.2^imb5/imb5; gl22Tg/gl22Tg	amputation: caudal fin	Figure 4 from Ong et al., 2020
regenerating fin neutrophil EGFP expression increased amount, abnormal	mfap4.2^imb5/imb5; gl22Tg/gl22Tg	amputation: caudal fin	Figure 4 from Ong et al., 2020
caudal fin neutrophil EGFP expression increased amount, abnormal	mfap4.2^imb5/imb5; gl22Tg/gl22Tg	standard conditions	Figure 4 from Ong et al., 2020

Citations